The goal of this study is to advance PTSD research by using novel multimodal magnetic resonance imaging (MRI) features including Read more
Rs-fMRI will be preprocessed according to the ENIGMA rs-fMRI pipeline [6] and parcellated using a high-resolution parcellation (such as the Read more
We will compare patients with PTSD (N~=1500) to trauma-exposed controls (N~=1500) from ENIGMA-PGC PTSD project on dynamic rsFC based on Read more
a large PTSD study investigating within and between network resting state functional connectivity is needed to better understand the role Read more
In the present study, we aim to compare results from three different harmonization approaches (1) LME, (2) ComBat, and (3) Read more
the bulk of imaging research to-date has focused on these regions with respect to major symptoms of the disorder (i.e. Read more
We propose to utilize the resting-state fMRI data of the ENIGMA-PGC PTSD consortium to characterize topological organization of functional network Read more
In this study we propose to adopt a normative modeling/conformal prediction approach for examining neurobiological heterogeneity within PTSD patients. We Read more
We propose to use the ENIGMA-PTSD sample to conduct the largest confirmatory “mega-analysis” to test a priori hypotheses about the Read more
Determining the pathophysiology of posttraumatic stress disorder (PTSD) is a critical step toward reducing its debilitating impact. A key step Read more
A better neurobiological and network level understanding of PTSD can lead to diagnostic clarity and more advanced, targeted and individualized Read more
ITRED argues for a research and clinical focus on the unique symptomology of intrusive and involuntary recollection and re-experiencing the Read more
A hierarchical multi-site ICA model for investigating brain network difference in PTSD Read more
We propose to utilize the resting-state fMRI data of the ENIGMA-PGC PTSD consortium to characterize topological organization of functional network Read more
Read the default mode network subsystems for PTSD proposal from Boston University School of Medicine
Recent evidence suggests that individuals with PTSD show disrupted functional connectivity in the default mode network, an intrinsic network that Read more