ABSTRACT Genetic inputs that influence human cortical structure are governed by pervasive pleiotropy as evidenced by recent genome wide association studies (GWAS). This pleiotropy may be harnessed to realize unique …
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Read Mary Mufford’s abstract
Background: Posttraumatic stress disorder (PTSD) is a psychiatric disorder with considerable symptom heterogeneity and comorbidity that may develop after trauma exposure. The amygdala’s role in fear conditioning makes it an …
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Mike Yassa A. Research Question, Goal, or Specific Aims We have developed and published a pipeline for determining structural and connectivity data for the paraventricular nucleus (PVT) using 3T MRI …
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Suprateek Kundu, PhD A. Research Question, Goal, or Specific Aims This proposal develops state of the art approaches for addressing challenging questions related to the neurobiological mechanisms affecting clinical outcomes …
Read Aliaa Ibnidris’ Hippocampal / Amygdala Subfields Proposal
1. Summary of the research plan Anxiety and stressor-related disorders are major contributors to the global burden of disease and pose a great challenge on individuals, their loved ones, and …
Read Toledo’s Acute Trauma Proposal
A. Research Question, Goal, or Specific Aims Traumatic experiences cause acute posttraumatic stress symptoms (PTSS) in survivors, which can be exacerbated by comorbidly incurred mild to moderate traumatic brain injury …
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A. Research Question, Goal, or Specific Aims Where in the brain (on a voxel-by-voxel basis) is the gray and white matter volume different in patients with PTSD compared to a …
structural ProposalsRead Duke’s Cerebellar Volume Proposal
Cerebellar volume based structural alterations in PTSD I. Title: Cerebellar volume based structural alterations in PTSD II. Investigative Team: Ashley Huggins Melvin Briggs Delin Sun Sarah Laskowitz C. Lexi Baird …
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Identifying Sex-Dependent Connectivity patterns in Trauma and PTSD A. Research Question, Goal, or Specific Aims Aim 1: We plan to replicate our findings (Helpman et al., 2021) regarding sex-dependent functional …
Read Lauren Salminen’s abstract
PTSD and depression show unique trauma-related signatures in the hippocampal subfields: International analysis from the PGC-ENIGMA PTSD Working Group Lauren E. Salminen, Mark W. Logue, Yuanchao Zheng, Philipp Saemann, Emily …