Home 2021-07-08T20:27:33+00:00


Unraveling the Genetic Architecture of PTSD and Trauma Response


Check out the latest manuscript on gene expression! – Frontiers in Neuroscience 

A recent collaboration from the PGC-PTSD Physical Health working group explored the individual and synergistic contributions of PTSD symptoms and blood pressure genetics to blood pressure levels in trauma-exposed individuals – Frontiers in Neuroscience (Jun. 2021)

FreeSurfer‐based segmentation of hippocampal subfields: A review of methods and applications, with a novel quality control procedure for ENIGMA studies and other collaborative efforts – Human Brain Mapping (Dec. 2020)

Cortical volume abnormalities in posttraumatic stress disorder: an ENIGMA-psychiatric genomics consortium PTSD workgroup mega-analysis – Molecular Psychiatry (Nov. 2020)

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci  – Nature Communications (Oct. 2019)

Genomic Approaches to Posttraumatic Stress Disorder: the Psychiatric Genomic Consortium Initiative – Biological Psychiatry (Feb. 2018)

The world’s largest set of brain scans are helping reveal the workings of the mind and how diseases ravage the brain – ENIGMA in Science Magazine (Jan. 2018)

Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multi-Site ENIGMA-PGC Study – Biological Psychiatry (Feb. 2018)


Check out Carissa Weis and colleagues’ latest poster “Data-driven approach to dynamic resting state functional connectivity: an ENIGMA-PGC PTSD study” here!  Carissa’s dissertation work is also presented using the R shiny app here. Check out Gopalkumar Rakesh, MD’s latest poster ‘Thalamic Nuclei Volumes in Posttraumatic Stress Disorder: A Multisite PCG-ENIGMA PTSD Study’ here! Read the abstract for “Data-driven approach to dynamic resting state functional connectivity: an ENIGMA-PGC PTSD study” by Carissa Weis and colleagues here! Read “ENIGMA HALFpipe: Interactive, reproducible, and efficient analysis for resting-state and task based fMRI data” by Lea Waller and colleagues here! ‘Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts‘ has been accepted at Cell Reports. This is the first publication from the PGC-PTSD Systems Biology workgroup! DTI neuroimaging paper ‘Altered White Matter Microstructural Organization in Post-Traumatic Stress Disorder across 3,047 Adults: Results from the PGC-ENIGMA PTSD Consortium’ has been accepted at Biological Psychiatry. PGC-PTSD Freeze 2 summary data now available! See Access Data to learn more.




Stay tuned!


Cohen Veteran’s Bioscience symposium at ISTSS, November 2019 PGC dinner at WCPG, October 2019 Face-to-face PGC-PTSD Meeting at SOBP, May 2018 PGC dinner at WCPG, October 2018 Cohens Veterans Care Summit: Upcycle, October 2018  RAPID-Dx Consensus Conference: May 2017 Cohen Veterans Bioscience Meeting: October 2017